Allergy and Immunology Research

This page includes an alphabetical listing of current allergy and immunology research projects, that AIFA have been advised of, in Australia and New Zealand. These projects are in addition to the AIFA and ASCIA funded projects listed at www.allergyimmunology.org.au/projects

AADRY - Australian Autoinflammatory Diseases RegistrY Study

The Australian Autoinflammatory Diseases RegistrY (AADRY) study, coordinated through the Walter and Eliza Hall Institute of Medical Research (WEHI) aims to establish a national registry of patients with suspected and confirmed monogenic autoinflammatory diseases, and to provide whole exome sequencing and immunological evaluation of novel variants as an investigative tool for patients who have an autoinflammatory phenotype but remain without a genetic diagnosis. If you are caring for a patient that you suspect has an autoinflammatory disease or for one with a confirmed diagnosis, please contact This email address is being protected from spambots. You need JavaScript enabled to view it. 

ANZADA - Australia and New Zealand Antibody Deficiency Allele Study

ANZADA is a national collaborative research project supported by the NHMRC that aims to identify the cellular and genetic causes of antibody deficiency diseases, including CVID, IgA deficiency, and specific antibody deficiency. The study is recruiting patients of any age with any of these disorders.  For more information email This email address is being protected from spambots. You need JavaScript enabled to view it. 

APOSLE - Australia point mutation in SLE Study

APOSLE is a national collaborative research project supported by the NHMRC that aims to identify the cellular and genetic causes of systemic lupus erythematosus. For more information email This email address is being protected from spambots. You need JavaScript enabled to view it.

BEAT - Beating Egg Allergy Trial

The BEAT trial is investigating the effect of early introduction of egg into the diet of infants at high risk for atopy and subsequent egg allergy.  For more information email This email address is being protected from spambots. You need JavaScript enabled to view it.

Centre for Food & Allergy Research (CFAR)

A collaborative group of Australian allergy researchers are involved in an NHMRC funded national Centre for Food & Allergy Research (CFAR), which aims to curb the food allergy epidemic. For more information email This email address is being protected from spambots. You need JavaScript enabled to view it. or go to www.foodallergyresearch.org.au

CVID Study

This study aims to find the cause of common variable immunodeficiency (CVID) and is being conducted by researchers at the Walter and Eliza Hall Institute and the Royal Melbourne Hospital. If you are aged between 18 and 80 and have been diagnosed with CVID or XLA, you are eligible to participate.  For more information go to www.wehi.edu.au/PIDdonor

DOMInO 6 (DHA to Optimise Maternal and Infant Outcomes 6 year follow up study)

This is a 6 year follow up of children born to mothers in the DOMInO study, a randomised controlled trial to investigate the effect of maternal supplementation with omega-3 long chain poly-unsaturated fatty acids (LCPUFA) in pregnancy on clinical outcomes of allergic disease in the child.  For more information email This email address is being protected from spambots. You need JavaScript enabled to view it. 

Immune milk proteins for the treatment of eczema

Immune proteins in milk have shown promise in pre-clinical studies to improve the symptoms of eczema. The aim of this study being run at the St George Dermatology and Skin Cancer Centre in Sydney is to determine if enriched milk proteins taken as a supplement for 8 weeks reduce the severity of eczema symptoms. The study is now recruiting participants with eczema. For more information email This email address is being protected from spambots. You need JavaScript enabled to view it. or go to http://app.griffith.edu.au/news/2014/06/12/using-milk-proteins-to-treat-eczema/

Oral peanut immunotherapy with modified dietary starch adjuvant (OPIA) trial

The Children’s Hospital at Westmead (CHW) OPIA research team has recently commenced recruitment for an oral peanut immunotherapy (OIT) trial for children aged 10-16 years with a diagnosed peanut allergy, who are able to travel to CHW every 2-3 weeks. This trial focuses on using small dose peanut challenges along with a dietary fibre supplement to train the body to become tolerant to peanut. The dietary supplement of high-amylase maize starch with a short chain fatty acid is called butyrate. Developed by the CSIRO, it is easily mixed into a range of foods. The duration of the study for most participants will be measured over one year.

Please visit www.schn.health.nsw.gov.au/research/clinical-trials/peanut-allergy-trial to obtain information packs for eligible patients.  If you have any questions please email the OPIA research team This email address is being protected from spambots. You need JavaScript enabled to view it.

TiARA - Tick induced Allergies Research and Awareness

This research and educational fund has been established at Royal North Shore Hospital, Sydney, NSW. For more information email This email address is being protected from spambots. You need JavaScript enabled to view it. or write to Clinical A/Professor Sheryl van Nunen, Department of Clinical Immunology and Allergy, Royal North Shore Hospital St Leonards NSW 2065 

Content updated November 2018

©2018 Allergy and Immunology Foundation of Australasia